A Class I HDAC Inhibitor BG45 Alleviates Cognitive Impairment through the CaMKII/ITPKA/Ca²⁺ Signaling Pathway

• Main Authors: Jingyun Liu (Author), Chenghong Zhang (Author), Jiale Wang (Author), Yufei Huang (Author), Di Shen (Author), Yingqiu Hu (Author), Haiying Chu (Author), Xuebin Yu (Author), Liyuan Zhang (Author), Haiying Ma (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) seriously endangers the health and life of elderly individuals worldwide. However, despite all scientific efforts, at the moment there are no effective clinical treatment options for AD. In this work, the effect of the class I histone deacetylase inhibitor (HDACI) BG45...