UJI TOKSISITAS SUBKRONIS EKSTRAK CURCUMA BEBAS MINYAK ATSIRI (ECBA) DITINJAU DARI PARAMETER PROFIL LEUKOSIT PADA TIKUS PUTIH GALUR WISTAR

The effect of Volatil Oil of Curcuma Extraxt or Curcumin extract with centration of essential oil in reducing the levels of cholesterol in the blood has been ECBA as antihyperlipidemic agent is given for a long - term therapeutic purpose. This experiment was performed to investigate the subchronic t...

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Bibliographic Details
Main Authors: Verda Farida (Author), Zullies Ikawati (Author), Suwidjiyo Pramono (Author)
Format: Book
Published: Universitas Ahmad Dahlan, 2014-05-01T00:00:00Z.
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Summary:The effect of Volatil Oil of Curcuma Extraxt or Curcumin extract with centration of essential oil in reducing the levels of cholesterol in the blood has been ECBA as antihyperlipidemic agent is given for a long - term therapeutic purpose. This experiment was performed to investigate the subchronic toxicity of ECBA on leukocytes profile of Wistar rats. ECBA was investigated at dose 15 mg, 120 mg, and 960 mg/200 g body weight for 90 days in 40 male Wistar rats. CMC-Na was used for control. The blood was examined for the leukocytes profile on day 0, 45, and 90. The rats were still maintained under experimental conditions without giving ECBA until day 105 for the reversibility test. The result showed that the administration of ECBA for 90 days did not affect leukocytes profile of Wistar rats.
Item Description:10.12928/pharmaciana.v4i1.398
2088-4559
2477-0256