Preparation of MSZ Hydrogel and Its Treatment of Colitis

• Main Authors: Yanhong Wu (Author), Shangyong Li (Author), Mengfei Jin (Author), Dandan Li (Author), Zihan Zhou (Author), Haiqing Hou (Author), Yantao Han (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to control the release of mesalazine (MSZ) in the gastrointestinal tract to achieve better pharmacological effects in the colon, in this study, MSZ was added to hydroxypropyl-β-cyclodextrin (HP-β-CD) to form a water-soluble HP-β-CD/MSZ inclusion complex. Then, the inclusion compound was loa...