Single-cell chromatin accessibility of developing murine pancreas identifies cell state-specific gene regulatory programs

• Main Authors: Sean de la O (Author), Xinkai Yao (Author), Sean Chang (Author), Zhe Liu (Author), Julie B. Sneddon (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Numerous studies have characterized the existence of cell subtypes, along with their corresponding transcriptional profiles, within the developing mouse pancreas. The upstream mechanisms that initiate and maintain gene expression programs across cell states, however, remain largely unknown. Here, we...