Clinical, biochemical and hormone profile in hirsute vs nonhirsute patients with polycystic ovary syndrome
Background: Polycystic ovary syndrome (PCOS), a common endocrinopathy present with variety of phenotypes with broad spectrum of clinical symptoms. Hyperandrogenism characterized with the presence of hirsutism remains an important feature of PCOS. Aim: The present study was conducted to assess differ...
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| Main Authors: | , , , |
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| Format: | Book |
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Barpeta Obstetrics and Gynaecological Society,
2020-07-01T00:00:00Z.
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| Summary: | Background: Polycystic ovary syndrome (PCOS), a common endocrinopathy present with variety of phenotypes with broad spectrum of clinical symptoms. Hyperandrogenism characterized with the presence of hirsutism remains an important feature of PCOS. Aim: The present study was conducted to assess difference in the clinical, biochemical and hormone profile in hirsute and non-hirsute females with PCOS. Methods: Detailed physical and clinical history was taken in all subjects. Hormonal and biochemical assays were performed by ECLIA. Results: 105 normoglycemic cases were enrolled for this study. The mean age of patients was 22.19 ±4.4 years and the mean age of menarche was 13.3±1.4 years. Acne was present in more than 50% of our cases. 81% cases were hirsute and only 19% were non-hirsute. Mean fasting blood glucose and triglycerides were found to be statistically significant between the two groups. A positive trend of hirsutism was found to be associated with irregular cycles and family history of type-2 diabetes mellitus (T2DM). Conclusion: The mean blood glucose and triglycerides was elevated in hirsute PCOS, while as BMI, weight and waist circumference was slightly elevated in non-hirsute PCOS females. |
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| Item Description: | 10.21276/obgyn.2020.7.8 2454-2334 2454-2342 |