Comprehensive In Vitro and In Silico Aerodynamic Analysis of High-Dose Ibuprofen- and Mannitol-Containing Dry Powder Inhalers for the Treatment of Cystic Fibrosis

• Egile Nagusiak: Petra Party (Egilea), Zsófia Ilona Piszman (Egilea), Árpád Farkas (Egilea), Rita Ambrus (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<b>Background:</b> Cystic fibrosis is a hereditary disease, which causes the accumulation of dense mucus in the lungs accompanied by frequent local inflammation. The non-steroidal anti-inflammatory drug ibuprofen (IBU) and the mucolytic mannitol (MAN) can treat these symptoms. Compared t...