In vitro and in vivo evaluation of didymin cyclodextrin inclusion complexes: characterization and chemosensitization activity

• Main Authors: Qing Yao (Author), Meng-Ting Lin (Author), Qing-Hua Lan (Author), Zhi-Wei Huang (Author), Ya-Wen Zheng (Author), Xue Jiang (Author), Yin-Di Zhu (Author), Longfa Kou (Author), He-Lin Xu (Author), Ying-Zheng Zhao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Didymin is a dietary flavonoid that first found in citrus fruits, and possesses antioxidant properties. Our preliminary experiments first discovered that didymin was able to sensitize the resistant cancer cells against chemotherapeutics and combat multidrug resistance. However, its poor aqueous solu...