Comparative assessment of topical steroids, topical tretenoin (0.05%) and dithranol paste in alopecia areata
<b>Background:</b> There have been various controversial reports regarding the efficacy of topical agents in topical therapy of alopecia areata. <b> Aim:</b> The study aims to find out the effective ones among the readily available ones for a dermatologist. <b> Material...
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| Main Authors: | , , , |
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| Format: | Book |
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Wolters Kluwer Medknow Publications,
2010-01-01T00:00:00Z.
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| Summary: | <b>Background:</b> There have been various controversial reports regarding the efficacy of topical agents in topical therapy of alopecia areata. <b> Aim:</b> The study aims to find out the effective ones among the readily available ones for a dermatologist. <b> Materials and Methods:</b> Eighty patients were chosen from the skin OPD of Bankura Sammilani Medical College, Bankura, West Bengal, after evaluating the exclusion criterions. Treatments were continued for 3 month period and a follow up after further 3 months. After dividing them into four groups-group-I (topical steroids), group-II (topical tretinoin 0.05%) group-III (dithranol paste 0.25%), and group-IV (white soft petrolatum jelly)-patients were evaluated. <b> Results:</b> Seventy percent of group-I, 55% of group-II, 35% of group-III, and 20% of the control group (white soft petrolatum jelly) responded favorably. Side effects in the form of dermatitis and hyperpigmentation were seen in group-III. However, no patient discontinued from the study. <b> Conclusion:</b> We conclude that both topical steroids and tretinoin were fairly effective in limited variant of alopecia areata. |
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| Item Description: | 0019-5154 1998-3611 |