Synthesis, Antibacterial and Antiribosomal Activity of the 3<i>C</i>-Aminoalkyl Modification in the Ribofuranosyl Ring of Apralogs (5-<i>O</i>-Ribofuranosyl Apramycins)
The synthesis and antiribosomal and antibacterial activity of both anomers of a novel apralog, 5-<i>O</i>-(5-amino-3-<i>C</i>-dimethylaminopropyl-D-ribofuranosyl)apramycin, are reported. Both anomers show excellent activity for the inhibition of bacterial ribosomes and that o...
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Main Authors: | Dmitrijs Lubriks (Author), Klara Haldimann (Author), Sven N. Hobbie (Author), Andrea Vasella (Author), Edgars Suna (Author), David Crich (Author) |
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Format: | Book |
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MDPI AG,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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