Synthesis of some bis-triazole derivatives as probes for cytotoxicity study
A series of bis-[4-N-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes (1a-e) and their Schiff bases with 2-adamanta-none (2a-d) and bis - [1, 2, 4-triazolo [3, 4-b] - 1, 3, 4-thiadiazol-4-yl] alkanes (3a-e) have been synthesized with high yields. The cytotoxicity study of these newly synthesized compoun...
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मुख्य लेखक: | |
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स्वरूप: | पुस्तक |
प्रकाशित: |
Bangladesh Pharmacological Society,
2006-06-01T00:00:00Z.
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विषय: | |
ऑनलाइन पहुंच: | Connect to this object online. |
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सारांश: | A series of bis-[4-N-amino-5-mercapto-1,2,4-triazol-3-yl] alkanes (1a-e) and their Schiff bases with 2-adamanta-none (2a-d) and bis - [1, 2, 4-triazolo [3, 4-b] - 1, 3, 4-thiadiazol-4-yl] alkanes (3a-e) have been synthesized with high yields. The cytotoxicity study of these newly synthesized compounds against brine shrimp lethality test as well as Structure-Activity-Relationship (SAR) has been discussed. |
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वस्तु वर्णन: | 1991-007X 1991-0088 |