Identification of Schistosoma haematobium and Schistosoma mansoni linear B-cell epitopes with diagnostic potential using in silico immunoinformatic tools and peptide microarray technology.

• Main Authors: Arthur Vengesai (Author), Marble Manuwa (Author), Herald Midzi (Author), Masimba Mandeya (Author), Victor Muleya (Author), Keith Mujeni (Author), Isaac Chipako (Author), Takafira Mduluza (Author)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2024-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<h4>Introduction</h4>Immunoinformatic tools can be used to predict schistosome-specific B-cell epitopes with little sequence identity to human proteins and antigens other than the target. This study reports an approach for identifying schistosome peptides mimicking linear B-cell epitopes...