Pharmacogenetic variability of tuberculosis biomarkers in native and mestizo Peruvian populations

• Main Authors: Luis Jaramillo‐Valverde (Author), Kelly S. Levano (Author), David D. Tarazona (Author), Silvia Capristano (Author), Cesar Sanchez (Author), Julio A. Poterico (Author), Eduardo Tarazona‐Santos (Author), Heinner Guio (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract In Peru, 29 292 people were diagnosed with tuberculosis in 2022. Although tuberculosis treatments are effective, 3.4%-13% are associated with significant adverse drug reactions, with drug‐induced liver injury (DILI) considered the most predominant. Among the first‐line antituberculosis drug...