3D disorganization and rearrangement of genome provide insights into pathogenesis of NAFLD by integrated Hi-C, Nanopore, and RNA sequencing

• প্রধান লেখক: Lina Xu (লেখক), Lianhong Yin (লেখক), Yan Qi (লেখক), Xuemei Tan (লেখক), Meng Gao (লেখক), Jinyong Peng (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2021-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The three-dimensional (3D) conformation of chromatin is integral to the precise regulation of gene expression. The 3D genome and genomic variations in non-alcoholic fatty liver disease (NAFLD) are largely unknown, despite their key roles in cellular function and physiological processes. High-through...