Identification and characterization of the Onchocerca volvulus Excretory Secretory Product Ov28CRP, a putative GM2 activator protein.

• Main Authors: Ferdinand Ngale Njume (Author), Stephen Mbigha Ghogomu (Author), Robert Adamu Shey (Author), Lea Olive Tchouate Gainkam (Author), Philippe Poelvoorde (Author), Perrine Humblet (Author), Joseph Kamgno (Author), Annie Robert (Author), Leon Mutesa (Author), Christophe Lelubre (Author), Evelina Edelweiss (Author), Arnaud Poterszman (Author), Susi Anheuser (Author), Luc Vanhamme (Author), Jacob Souopgui (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Onchocerca volvulus is the nematode pathogen responsible for human onchocerciasis also known as "River blindness", a neglected tropical disease that affects up to 18 million people worldwide. Helminths Excretory Secretory Products (ESPs) constitute a rich repertoire of molecules that can b...