D-optimal Design for Preparation and Optimization of Fast Dissolving Bosentan Nanosuspension
Purpose: Bosentan is a drug currently taken orally for the treatment of pulmonary arterialhypertension. However, the water solubility of bosentan is very low, resulting in lowbioavailability. The aim of this study was preparation and optimization of bosentannanosuspension to improve solubility and d...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Tabriz University of Medical Sciences,
2016-06-01T00:00:00Z.
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