Cover Image

DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status

Intervertebral disc (IVD) degeneration is the primary cause for low back pain that has a high prevalence in modern society and poses enormous economic burden on patients. Few effective therapeutic strategies are available for IVD degeneration treatment. To understand the biological effects of dental...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xiwen Dong (Author), Fanqi Hu (Author), Jing Yi (Author), Yuning Zhang (Author), Chao Liu (Author), Panpan Geng (Author), Han Duan (Author), Chu-Tse Wu (Author), Xuesong Zhang (Author), Hua Wang (Author)
Format:	Book
Published:	Hindawi Limited, 2022-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Effects of puerarin on the intervertebral disc degeneration and biological characteristics of nucleus pulposus cells
by: Hengtao Tang, et al.
Published: (2023)

Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo
by: Wang H, et al.
Published: (2020)

The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration
by: Chang Liu, et al.
Published: (2021)

Mesenchymal Stem Cells May Alleviate the Intervertebral Disc Degeneration by Reducing the Oxidative Stress in Nucleus Pulposus Cells
by: Yongzhao Zhao, et al.
Published: (2022)

Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration in vivo
by: Huiyong Liu, et al.
Published: (2018)

The Onset of Systemic Lupus Erythematosus Triggers Nucleus Pulposus Cell Pyroptosis to Exacerbate Intervertebral Disc Degeneration
by: Lao Z, et al.
Published: (2024)

Morroniside attenuates nucleus pulposus cell senescence to alleviate intervertebral disc degeneration via inhibiting ROS-Hippo-p53 pathway
by: Chengcong Zhou, et al.
Published: (2022)

BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells
by: Quan Xiao, et al.
Published: (2022)

Decellularized nucleus pulposus matrix/chitosan hybrid hydrogel combined with nucleus pulposus stem cells and GDF5-loaded microspheres for intervertebral disc degeneration prevention
by: Tao Ma, et al.
Published: (2024)

Integrated transcriptome and proteome analyses identify novel regulatory network of nucleus pulposus cells in intervertebral disc degeneration
by: Chen Xu, et al.
Published: (2021)

Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration via inhibition of the MAPK/NF-κB signaling pathway
by: Huan Yang, et al.
Published: (2022)

Cyanidin attenuates the apoptosis of rat nucleus pulposus cells and the degeneration of intervertebral disc via the JAK2/STAT3 signal pathway in vitro and in vivo
by: Xiaoliang Bai, et al.
Published: (2022)

BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity
by: Xiao-Jun Yu, et al.
Published: (2023)

Augmented Cornus officinalis Levels in Liuwei Dihuang Decoction Inhibits Nucleus Pulposus Cell Pyroptosis to Enhance Therapeutic Efficacy Against Intervertebral Disc Degeneration
by: Ge Y, et al.
Published: (2024)

Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats
by: Feng Wang, et al.
Published: (2019)

Dehydrocostus Lactone Attenuates the Senescence of Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration via Inhibition of STING-TBK1/NF-κB and MAPK Signaling
by: Zhiqian Chen, et al.
Published: (2021)

Effect of Fas and Bcl-2 DNA Damages Response Expression in Stem Cells on Apoptosis of Nucleus Pulposus of Intervertebral Disc
by: Hui Zhang, et al.
Published: (2023)

The Differential Effects of Leukocyte-Containing and Pure Platelet-Rich Plasma on Nucleus Pulposus-Derived Mesenchymal Stem Cells: Implications for the Clinical Treatment of Intervertebral Disc Degeneration
by: Jun Jia, et al.
Published: (2018)

Bushen Huoxue Formula Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation in the Nucleus Pulposus Cells and Improves Intervertebral Disc Degeneration in Rats
by: Gao S, et al.
Published: (2024)

Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration
by: Jialiang Lin, et al.
Published: (2019)

The Survival of Human Intervertebral Disc Nucleus Pulposus Cells under Oxidative Stress Relies on the Autophagy Triggered by Delphinidin
by: Md Entaz Bahar, et al.
Published: (2024)

Sinapic Acid Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration
by: Huang JF, et al.
Published: (2020)

Intervertebral disc degeneration and regenerative medicine
by: Mariam Farag, et al.
Published: (2024)

Retracted: Effect of Fas and Bcl-2 DNA Damages Response Expression in Stem Cells on Apoptosis of Nucleus Pulposus of Intervertebral Disc
by: Stem Cells International
Published: (2024)

Hypo-Osmotic Loading Induces Expression of IL-6 in Nucleus Pulposus Cells of the Intervertebral Disc Independent of TRPV4 and TRPM7
by: Aleksandra Sadowska, et al.
Published: (2020)

Sirtuins in intervertebral disc degeneration: current understanding
by: Jianlin Shen, et al.
Published: (2024)

Bioenergetic dysfunction in the pathogenesis of intervertebral disc degeneration
by: Chao Song, et al.
Published: (2024)

Role of Autophagy and Pyroptosis in Intervertebral Disc Degeneration
by: Wang Z, et al.
Published: (2024)

Lumbar intervertebral disc degeneration in collegiate rowers
by: Chie Sekine, et al.
Published: (2014)

Unveiling the Gut-Disc Axis: How Microbiome Dysbiosis Accelerates Intervertebral Disc Degeneration
by: Sun Y, et al.
Published: (2024)

Effects of Stromal Cell-Derived Factor-1α Secreted in Degenerative Intervertebral Disc on Activation and Recruitment of Nucleus Pulposus-Derived Stem Cells
by: Jinwei Ying, et al.
Published: (2019)

Cutting-Edge Biomaterials in Intervertebral Disc Degeneration Tissue Engineering
by: Yifan Wang, et al.
Published: (2024)

FOXO3-Activated circFGFBP1 Inhibits Extracellular Matrix Degradation and Nucleus Pulposus Cell Death via miR-9-5p/BMP2 Axis in Intervertebral Disc Degeneration In Vivo and In Vitro
by: Yanlin Tan, et al.
Published: (2023)

Intervertebral disc degeneration-Current therapeutic options and challenges
by: Ankita Samanta, et al.
Published: (2023)

INTERVERTEBRAL DISC DEGENERATION LINKED TO STRUCTURAL GENE VARIATIONS
by: Shahzad Shoukat Nayani, et al.
Published: (2024)

Regulatory Effect of Inflammatory Mediators in Intervertebral Disc Degeneration
by: Zhangfu Li, et al.
Published: (2023)

Degeneration and regeneration of the intervertebral disc: lessons from development
by: Lachlan J. Smith, et al.
Published: (2011)

Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways
by: Li B, et al.
Published: (2022)

Gene expression profiling in nucleus pulposus of human ruptured lumbar disc herniation
by: Xiaochun Li, et al.
Published: (2022)

Aging, cell senescence, the pathogenesis and targeted therapies of intervertebral disc degeneration
by: Jiongnan Xu, et al.
Published: (2023)