Cover Image

Discovery and efficacy study of an ALK inhibitor AMX6001 in anaplastic large cell lymphoma Karpas299 mice models

Anaplastic lymphoma kinase (ALK) is an attractive therapeutic target for the treatment of anaplastic large cell lymphoma (ALCL). We identified novel deuterated 2,4-diarylamino pyrimidine compounds as potent ALK inhibitors. The compound 9 (AMX6001) showed better in vitro activity against ALK and NPM-...

Full description

Saved in:
Bibliographic Details
Main Authors: Debasis Das (Author), Lingzhi Xie (Author), Dandan Qiao (Author), Yuxi Cao (Author), Jianhe Jia (Author), Yong Li (Author), Jian Hong (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items