Population Pharmacodynamic Modeling of Epoetin Alfa in End‐Stage Renal Disease Patients Receiving Maintenance Treatment Using Bayesian Approach

• Hauptverfasser: Ly Minh Nguyen (VerfasserIn), Calvin J. Meaney (VerfasserIn), Gauri G. Rao (VerfasserIn), Mandip Panesar (VerfasserIn), Wojciech Krzyzanski (VerfasserIn)
• Format: Buch
• Veröffentlicht: Wiley, 2020-10-01T00:00:00Z.
• Schlagworte: article
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The ability to control dosage regimens of erythropoiesis‐stimulating agents (ESAs) to maintain a desired hemoglobin (HGB) target is still elusive. We utilized a Bayesian approach and informative priors to characterize HGB profiles, using simulated drug concentrations, in patients with end‐stage rena...