Platelet gene therapy induces robust immune tolerance even in a primed model via peripheral clonal deletion of antigen-specific T cells
While platelet-specific gene therapy is effective in inducing immune tolerance to a targeted protein, how the reactivity of pre-existing immunity affects the efficacy, and whether CD8 T cells were involved in tolerization, is unclear. In this study, ovalbumin (OVA) was used as a surrogate protein. P...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2021-03-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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