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Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

Although chemotherapy, targeted therapy and endocrine therapy decrease rate of disease recurrence in most breast cancer patients, many patients exhibit acquired resistance. Hyperactivation of the PI3K/AKT/mTOR pathway is associated with drug resistance and cancer progression. Currently, a number of...

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Bibliographic Details
Main Authors: Chao Dong (Author), Jiao Wu (Author), Yin Chen (Author), Jianyun Nie (Author), Ceshi Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
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