Photobactericides-A Local Option against Multi-Drug Resistant Bacteria
The use of light-activated bactericidal agents-photobactericides-is suggested in local infection in order to conserve conventional antibacterials for more systemic disease. Local administration of a photobactericide such as methylene blue coupled with locally-targeted red light illumination ensures...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
MDPI AG,
2013-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | The use of light-activated bactericidal agents-photobactericides-is suggested in local infection in order to conserve conventional antibacterials for more systemic disease. Local administration of a photobactericide such as methylene blue coupled with locally-targeted red light illumination ensures the production of non-specific reactive oxygen species and thus a rapid and localised antibacterial response, regardless of the conventional resistance status. To this end, the response of photobactericides to conventional resistance mechanisms, and their potential use in infection, is discussed. |
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| Item Description: | 10.3390/antibiotics2020182 2079-6382 |