The pH-Insensitive Antimicrobial and Antibiofilm Activities of the Frog Skin Derived Peptide Esc(1-21): Promising Features for Novel Anti-Infective Drugs

• Main Authors: Maria Rosa Loffredo (Author), Floriana Cappiello (Author), Giacomo Cappella (Author), Elisabetta Capuozzo (Author), Luisa Torrini (Author), Fabiana Diaco (Author), Yuanpu Peter Di (Author), Maria Luisa Mangoni (Author), Bruno Casciaro (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The number of antibiotic-resistant microbial infections is dramatically increasing, while the discovery of new antibiotics is significantly declining. Furthermore, the activity of antibiotics is negatively influenced by the ability of bacteria to form sessile communities, called biofilms, and by the...