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Quantitative Study of Impurities in Bedaquiline Fumarate: Identification and Characterization of Its Three Degradation Products Using HPLC, LC/ESI-MS, and NMR Analyses

Abstract The study aimed to establish a high-performance liquid chromatography (HPLC) method for the quantitative analysis of the related substances of bedaquiline fumarate. Nuclear magnetic resonance and mass spectrometry were used for characterization and assay. A chromatographic method was used f...

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Main Authors:	Xiao-Wen Zhang (Author), Gang-Long Jiang (Author), Guo-Jing Li (Author), Xiao-Yan Chen (Author), Ai-Nan Zhou (Author), Yu Liu (Author)
Format:	Book
Published:	Georg Thieme Verlag KG, 2023-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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