p16 as an independent marker for detection of high-risk HPV in oral submucous fibrosis and oral squamous cell carcinoma
Background: An alarming increase in incidence of high-risk human papillomavirus (HPV) positive tumors in head and neck squamous cell carcinoma (HNSCC) by 25% and 70% in oropharyngeal HNSCC cannot be ignored. The early oncogenes of HPV, E6, and E7 play a key role in carcinogenesis. HPV associated tum...
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Wolters Kluwer Medknow Publications,
2019-01-01T00:00:00Z.
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