Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• المؤلفون الرئيسيون: Lucía Sanjurjo (مؤلف), Esmeralda Castelblanco (مؤلف), Josep Julve (مؤلف), Nuria Villalmanzo (مؤلف), Érica Téllez (مؤلف), Anna Ramirez-Morros (مؤلف), Núria Alonso (مؤلف), Dídac Mauricio (مؤلف), Maria-Rosa Sarrias (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...