Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• Prif Awduron: Lucía Sanjurjo (Awdur), Esmeralda Castelblanco (Awdur), Josep Julve (Awdur), Nuria Villalmanzo (Awdur), Érica Téllez (Awdur), Anna Ramirez-Morros (Awdur), Núria Alonso (Awdur), Dídac Mauricio (Awdur), Maria-Rosa Sarrias (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2023-05-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...