Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• Hauptverfasser: Lucía Sanjurjo (Verfasst von), Esmeralda Castelblanco (Verfasst von), Josep Julve (Verfasst von), Nuria Villalmanzo (Verfasst von), Érica Téllez (Verfasst von), Anna Ramirez-Morros (Verfasst von), Núria Alonso (Verfasst von), Dídac Mauricio (Verfasst von), Maria-Rosa Sarrias (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...