Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• Päätekijät: Lucía Sanjurjo (Tekijä), Esmeralda Castelblanco (Tekijä), Josep Julve (Tekijä), Nuria Villalmanzo (Tekijä), Érica Téllez (Tekijä), Anna Ramirez-Morros (Tekijä), Núria Alonso (Tekijä), Dídac Mauricio (Tekijä), Maria-Rosa Sarrias (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...