Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• Auteurs principaux: Lucía Sanjurjo (Auteur), Esmeralda Castelblanco (Auteur), Josep Julve (Auteur), Nuria Villalmanzo (Auteur), Érica Téllez (Auteur), Anna Ramirez-Morros (Auteur), Núria Alonso (Auteur), Dídac Mauricio (Auteur), Maria-Rosa Sarrias (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...