Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• मुख्य लेखकों: Lucía Sanjurjo (लेखक), Esmeralda Castelblanco (लेखक), Josep Julve (लेखक), Nuria Villalmanzo (लेखक), Érica Téllez (लेखक), Anna Ramirez-Morros (लेखक), Núria Alonso (लेखक), Dídac Mauricio (लेखक), Maria-Rosa Sarrias (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...