Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• Main Authors: Lucía Sanjurjo (Author), Esmeralda Castelblanco (Author), Josep Julve (Author), Nuria Villalmanzo (Author), Érica Téllez (Author), Anna Ramirez-Morros (Author), Núria Alonso (Author), Dídac Mauricio (Author), Maria-Rosa Sarrias (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2023-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...