Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts

• Main Authors: Hongxu Lu (Author), Zhaoxia Zhang (Author), Zhaoying Wang (Author), Jinkui Wang (Author), Tao Mi (Author), Liming Jin (Author), Xin Wu (Author), Junyi Luo (Author), Yimeng Liu (Author), Junhong Liu (Author), Wenquan Cai (Author), Peng Guo (Author), Dawei He (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Long-term extensive use of glucocorticoids will lead to hormonal necrosis of the femoral head, and osteoblasts play an important role in the prevention of osteonecrosis. However, there is no complete cure for necrosis of the femoral head. Mesenchymal stem cell- (MSCs-) derived exosomes a...