SRC Kinase-Mediated Tyrosine Phosphorylation of TUBB3 Regulates Its Stability and Mitotic Spindle Dynamics in Prostate Cancer Cells

Tubulin is an integral part of the cytoskeleton and plays a pivotal role in cellular signaling, maintenance, and division. β-tubulin is also the molecular target for taxane compounds such as docetaxel (DTX) and cabazitaxel (CTX), both first-line treatments for several solid cancers. Increased expres...

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Bibliographic Details
Main Authors: Alan Alfano (Author), Jin Xu (Author), Xi Yang (Author), Dhanraj Deshmukh (Author), Yun Qiu (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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