Prevalence of tumor BRCA1 and BRCA2 dysfunction in unselected patients with ovarian cancer
Objective The therapeutic benefits of poly(ADP-ribose) polymerase inhibitors highlight the need to evaluate BRCA1/2 defects in tubal/ovarian cancer (OC). We sought to determine the pattern and disease characteristics associated with tumor BRCA1/2 mutations and BRCA1 methylation in women with OC. Met...
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Korean Society of Obstetrics and Gynecology,
2020-09-01T00:00:00Z.
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