Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels

• Главные авторы: Fiorenza Rancan (Автор), Hildburg Volkmann (Автор), Michael Giulbudagian (Автор), Fabian Schumacher (Автор), Jessica Isolde Stanko (Автор), Burkhard Kleuser (Автор), Ulrike Blume-Peytavi (Автор), Marcelo Calderón (Автор), Annika Vogt (Автор)
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• Опубликовано: MDPI AG, 2019-08-01T00:00:00Z.
• Предметы: article
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Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin. In this study, we compared the skin penetration of tacrolimus formulated in tNGs with a commercial 0.1% tacrol...