A rapid method for relative quantification of N-glycans from a therapeutic monoclonal antibody during trastuzumab biosimilar development
Glycosylation is a common post-translational modification and critical quality attribute that can modulate the efficacy of therapeutic proteins. In the production of monoclonal antibodies (mAbs), quantifying the glycoform profile is a vital characterization step. Traditional glycan analysis is time...
Saved in:
Main Authors: | Zaneer Segu (Author), Todd Stone (Author), Claudia Berdugo (Author), Anthony Roberts (Author), Emma Doud (Author), Yunsong Li (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2020-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A tailored lectin microarray for rapid glycan profiling of therapeutic monoclonal antibodies
by: Shen Luo, et al.
Published: (2024) -
Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies
by: Sara Carillo, et al.
Published: (2020) -
MYTHS AND FACTS OF BIOSIMILAR MONOCLONAL ANTIBODIES
by: João Gonçalves
Published: (2015) -
USP Reference Standard Monoclonal Antibodies: Tools to Verify Glycan Structure
by: Jingzhong Guo, et al.
Published: (2022) -
Glycan Profile Analysis of Engineered Trastuzumab with Rationally Added Glycosylation Sequons Presents Significantly Increased Glycan Complexity
by: Esteban Cruz, et al.
Published: (2021)