Progress of Actinidia chinensis Planch. root extract (acRoots) in cancer immunity

Abstract Actinidia chinensis Planch. root extract (acRoots) is a famous Chinese traditional medicine used in the treatment of a variety of diseases, such as tumours and cardiovascular diseases, etc. However, its therapeutic mechanisms remain unclear. In this review, the biological features of acRoot...

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Main Authors: Lingyan Wang (Author), Zheng Li (Author), Miaomiao Zhang (Author), Qi Shen (Author), Xuemei Zhang (Author)
Format: Book
Published: Wiley, 2023-02-01T00:00:00Z.
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100 1 0 |a Lingyan Wang  |e author 
700 1 0 |a Zheng Li  |e author 
700 1 0 |a Miaomiao Zhang  |e author 
700 1 0 |a Qi Shen  |e author 
700 1 0 |a Xuemei Zhang  |e author 
245 0 0 |a Progress of Actinidia chinensis Planch. root extract (acRoots) in cancer immunity 
260 |b Wiley,   |c 2023-02-01T00:00:00Z. 
500 |a 2768-0622 
500 |a 10.1002/ctd2.171 
520 |a Abstract Actinidia chinensis Planch. root extract (acRoots) is a famous Chinese traditional medicine used in the treatment of a variety of diseases, such as tumours and cardiovascular diseases, etc. However, its therapeutic mechanisms remain unclear. In this review, the biological features of acRoots and its chemical compositions are explored, including polysaccharides, triterpenes, phenols, flavonoids and so on. The pathogenesis of cancer involves not only genetic factors but also the microenvironment. Different types of immune cells, such as T cells, macrophages and neutrophils, play an essential role in cancer development, and acRoots was found to take part in modulating cancer immunity. Therefore, this article summarises its role in cancer immunity and unmasks the potential underlying mechanisms by incorporating our research on cancer immunity. 
546 |a EN 
690 |a acRoots 
690 |a cancer immunity 
690 |a kiwifruit 
690 |a monomer 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
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786 0 |n Clinical and Translational Discovery, Vol 3, Iss 1, Pp n/a-n/a (2023) 
787 0 |n https://doi.org/10.1002/ctd2.171 
787 0 |n https://doaj.org/toc/2768-0622 
856 4 1 |u https://doaj.org/article/6d13c3de7f7849d99a43d81f8902c1dd  |z Connect to this object online.