Management of Acute Kidney Injury in Extremely Low Birth Weight Infants

Acute kidney injury (AKI) is a common problem in the neonatal intensive care unit (NICU). Neonates born at <1,000 g (extremely low birth weight, ELBW) are at an increased risk of secondary associated comorbidities such as intrauterine growth restriction, prematurity, volume restriction, ischaemic...

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Main Authors: Aoife Branagan (Author), Caoimhe S. Costigan (Author), Maria Stack (Author), Cara Slagle (Author), Eleanor J. Molloy (Author)
Format: Book
Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
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100 1 0 |a Aoife Branagan  |e author 
700 1 0 |a Aoife Branagan  |e author 
700 1 0 |a Caoimhe S. Costigan  |e author 
700 1 0 |a Maria Stack  |e author 
700 1 0 |a Maria Stack  |e author 
700 1 0 |a Cara Slagle  |e author 
700 1 0 |a Cara Slagle  |e author 
700 1 0 |a Eleanor J. Molloy  |e author 
700 1 0 |a Eleanor J. Molloy  |e author 
700 1 0 |a Eleanor J. Molloy  |e author 
700 1 0 |a Eleanor J. Molloy  |e author 
245 0 0 |a Management of Acute Kidney Injury in Extremely Low Birth Weight Infants 
260 |b Frontiers Media S.A.,   |c 2022-03-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2022.867715 
520 |a Acute kidney injury (AKI) is a common problem in the neonatal intensive care unit (NICU). Neonates born at <1,000 g (extremely low birth weight, ELBW) are at an increased risk of secondary associated comorbidities such as intrauterine growth restriction, prematurity, volume restriction, ischaemic injury, among others. Studies estimate up to 50% ELBW infants experience at least one episode of AKI during their NICU stay. Although no curative treatment for AKI currently exists, recognition is vital to reduce potential ongoing injury and mitigate long-term consequences of AKI. However, the definition of AKI is imperfect in this population and presents clinical challenges to correct identification, thus contributing to under recognition and reporting. Additionally, the absence of guidelines for the management of AKI in ELBW infants has led to variations in practice. This review summarizes AKI in the ELBW infant and includes suggestions such as close observation of daily fluid balance, review of medications to reduce nephrotoxic exposure, management of electrolytes, maximizing nutrition, and the use of diuretics and/or dialysis when appropriate. 
546 |a EN 
690 |a preterm infant 
690 |a extremely low birth weight 
690 |a renal biomarkers 
690 |a hypertension 
690 |a acute kidney injury 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 10 (2022) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fped.2022.867715/full 
787 0 |n https://doaj.org/toc/2296-2360 
856 4 1 |u https://doaj.org/article/6d1a95eaac2f4ff0a945ec6335cdea45  |z Connect to this object online.