Dapagliflozin Protects Methamphetamine-Induced Cardiomyopathy by Alleviating Mitochondrial Damage and Reducing Cardiac Function Decline in a Mouse Model

• Main Authors: Shanqing He (Author), Yajun Yao (Author), Nan Yang (Author), Youcheng Wang (Author), Dishiwen Liu (Author), Zhen Cao (Author), Huiyu Chen (Author), Yuntao Fu (Author), Mei Yang (Author), Songjun Wang (Author), Guangjie He (Author), Qingyan Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Methamphetamine (METH)-induced cardiovascular toxicity has been attributed to its destructive effect on mitochondrial function at least to some extent. Previous studies highlighted the benefits of dapagliflozin (DAPA) on the cardiovascular system, but the response of METH-induced cardiom...