Metformin and the risk of dementia based on an analysis of 396,332 participants

• Main Authors: Shiliang Ji (Author), Xingxing Zhao (Author), Ruifang Zhu (Author), Yongchao Dong (Author), Lifeng Huang (Author), Taiquan Zhang (Author)
• Format: Book
• Published: SAGE Publishing, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: AMPK has attracted widespread interest as a potential therapeutic target for age-related diseases, given its key role in controlling energy homeostasis. Metformin (Met) has historically been used to treat Type 2 diabetes and has been shown to counteract age-related diseases. However, stu...