Papillary thyroid carcinoma: How much should the surgeon read from Fine needle aspiration cytology reports?
<b>Objective:</b> During routine fine needle aspiration cytodiagnosis of papillary thyroid carcinoma (PTC), a number of cases are diagnosed as suspicious; or it is suggested that PTC or a neoplasm be ruled out by histopathology. Since these diagnostic labels are likely to put the clinici...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Wolters Kluwer Medknow Publications,
2010-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | <b>Objective:</b> During routine fine needle aspiration cytodiagnosis of papillary thyroid carcinoma (PTC), a number of cases are diagnosed as suspicious; or it is suggested that PTC or a neoplasm be ruled out by histopathology. Since these diagnostic labels are likely to put the clinicians in a difficult situation while planning the management, this study aims to find out how much the surgeon should read from these reports. <b>Materials and Methods:</b> The patients were divided into two groups. Group A included 38 cases diagnosed as PTC or suspicious of PTC. Group B included 40 cases in which it was suggested that PTC/a neoplasm to be ruled out and non-neoplastic lesions with one or more cytologic features of PTC. The two groups were compared with clinical, imaging and cytomorphologic features. <b>Results:</b> A significant difference was observed with respect to age between Group A and Group B (<i>P</i><0.001). The frequency of the following five cytologic features was significantly higher in Group A: papillary formation (<i>P</i><0.001), psammoma bodies (<i>P</i>=0.054), fine nuclear chromatin (<i>P</i>=0.010), frequent nuclear grooves (<i>P</i><0.001) and intra-nuclear cytoplasmic inclusion (<i>P</i><0.001). Three or more of the five cytologic features were also reported in significantly higher number of Group A cases (<i>P</i><0.001). Majority (81.8%) of the cases with subsequent histology in Group A were confirmed as PTC as opposed to 7.7% in Group B (<i>P</i><0.001). <b>Conclusions:</b> Thus, cases with definitive cytodiagnosis of PTC and suggestive of PTC (Group A) should be taken much more seriously by the surgeons as compared to Group B cases. |
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| Item Description: | 0377-4929 0974-5130 |