Value of osteoprotegerin, RANKL, interleukin-17 in mechanisms of bone metabolism disorders

The relationship between osteoprotegerin, RANKL and interleukin-17 inthe mechanisms of abnormal remodeling of bone tissue during experimental periodontitis was studied in this work. Increased levels of RANKL and pro-inflammatory IL-17 were found, as well as a decrease in the serum osteoprotegerin co...

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Bibliographic Details
Main Author: V. F. Cheremisina (Author)
Format: Book
Published: Kazimierz Wielki University, 2017-07-01T00:00:00Z.
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Summary:The relationship between osteoprotegerin, RANKL and interleukin-17 inthe mechanisms of abnormal remodeling of bone tissue during experimental periodontitis was studied in this work. Increased levels of RANKL and pro-inflammatory IL-17 were found, as well as a decrease in the serum osteoprotegerin content of rat experimental rats. The revealed correlations between the level of interleukin-17, RANKL and osteoprotegerin indicate an important role of the studied cytokines in bone remodeling disorders during periodontitis.
Item Description:2391-8306