Kymriah® (tisagenlecleucel) - An overview of the clinical development journey of the first approved CAR-T therapy
The emergence of cell and gene therapies has dramatically changed the treatment paradigm in oncology and other therapeutic areas. Kymriah® (tisagenlecleucel), a CD19-directed genetically modified autologous T-cell immunotherapy, is currently approved in major markets for the treatment of relapsed/re...
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| Main Authors: | , , , |
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| Format: | Book |
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Taylor & Francis Group,
2023-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | The emergence of cell and gene therapies has dramatically changed the treatment paradigm in oncology and other therapeutic areas. Kymriah® (tisagenlecleucel), a CD19-directed genetically modified autologous T-cell immunotherapy, is currently approved in major markets for the treatment of relapsed/refractory (r/r) pediatric and young adult acute lymphoblastic leukemia, r/r diffuse large B-cell lymphoma, and r/r follicular lymphoma. This article presents a high-level overview of the clinical development journey of tisagenlecleucel, including its efficacy outcomes and safety considerations. |
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| Item Description: | 2164-5515 2164-554X 10.1080/21645515.2023.2210046 |