A study of liver function in females with toxic goiter by using 131I Rose Bengal

26 consecutive female patients with goiter their age range between 22 - 65 years. Nodular forms were 10 patients, diffuse goiter were16 patients, euthyroid form were 6 patients, with sign of thyrotoxicosis (severe thyrotoxicosis 11 patients, moderate 9 patients). Sensitive test, Rose Bengal conjugat...

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Bibliographic Details
Main Author: Adeeb Abass Al-Shami (Author)
Format: Book
Published: College of Pharmacy / Mustansiriyah University, 2008-06-01T00:00:00Z.
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Summary:26 consecutive female patients with goiter their age range between 22 - 65 years. Nodular forms were 10 patients, diffuse goiter were16 patients, euthyroid form were 6 patients, with sign of thyrotoxicosis (severe thyrotoxicosis 11 patients, moderate 9 patients). Sensitive test, Rose Bengal conjugated with 131I was used for evaluation the absorption& excretion by liver cells and intrahepatic blood circulation. The results showed increase blood flow, liver accumulation of isotope in 25% of the patients and in 45-50% of patients were normal. The excretion of conjugated Rose Bengal with 131I shows severe suppression of liver function in 2 cases. In this study we found an increasing the maximum accumulation time of isotope 131I in the liver, both in severe & moderate thyrotoxicosis.
Item Description:10.32947/ajps.v4i1.375
1815-0993
2959-183X