MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL DIAGNOSTIC OF GASTROINTESTINAL STROMAL TUMORS OF THE DIGESTIVE TRACT

• Main Authors: D.M. Nahorna (Author), O.G. Kuryk (Author), V.O. Yakovenko (Author), V.V. Bazdyrev (Author)
• Format: Book
• Published: Bogomolets National Medical University, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract arising from interstitial cells of Cajal, mainly in the stomach and small intestine. GIST have oncogenic mutations in KIT or PDGFRA gene in 85-90% of tumors. For diagnostic GIST is nessesary t...