Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia

• Autors principals: Bálint Egyed (Autor), Anna Horváth (Autor), Ágnes F. Semsei (Autor), Csaba Szalai (Autor), Judit Müller (Autor), Dániel J. Erdélyi (Autor), Gábor T. Kovács (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Central nervous system (CNS) involvement is a leading cause of therapy-refractory pediatric acute lymphoblastic leukemia (pALL), which is aggravated by underdiagnosing CNS disease with the currently used cell-based approach of cerebrospinal fluid (CSF) diagnostics. Our study focused on developing no...