Model‐Informed Drug Development for Everolimus Dosing Selection in Pediatric Infant Patients

Everolimus is currently approved in Europe as an adjunctive therapy for patients aged ≥ 2 years with tuberous sclerosis complex (TSC)-associated treatment‐refractory partial‐onset seizures, based on the EXIST‐3 study (NCT01713946) results. As TSC‐associated seizures can also affect children aged bet...

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Bibliographic Details
Main Authors: Francois Pierre Combes (Author), Heidi J. Einolf (Author), Neva Coello (Author), Tycho Heimbach (Author), Handan He (Author), Kai Grosch (Author)
Format: Book
Published: Wiley, 2020-04-01T00:00:00Z.
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