Hypereosinophilic syndrome presenting as eosinophilic gastroenteritis exacerbated by clopidogrel bisulphate

Clopidogrel is a widely prescribed prodrug with antithrombotic activity that functions by irreversibly inhibiting the P2Y12 receptors on platelets; nevertheless, drug-induced eosinophilia from this drug is rarely reported. An 81-year-old man was diagnosed with cerebral infarction 2 months earlier an...

Full description

Saved in:
Bibliographic Details
Main Authors: Horino Taro (Author), Ohnishi Hiroshi (Author), Komori Masahiro (Author), Terada Yoshio (Author)
Format: Book
Published: Sciendo, 2023-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_6e5b429e63e04e09a6dc0d02ed41c03c
042 |a dc 
100 1 0 |a Horino Taro  |e author 
700 1 0 |a Ohnishi Hiroshi  |e author 
700 1 0 |a Komori Masahiro  |e author 
700 1 0 |a Terada Yoshio  |e author 
245 0 0 |a Hypereosinophilic syndrome presenting as eosinophilic gastroenteritis exacerbated by clopidogrel bisulphate 
260 |b Sciendo,   |c 2023-12-01T00:00:00Z. 
500 |a 2501-062X 
500 |a 10.2478/rjim-2023-0022 
520 |a Clopidogrel is a widely prescribed prodrug with antithrombotic activity that functions by irreversibly inhibiting the P2Y12 receptors on platelets; nevertheless, drug-induced eosinophilia from this drug is rarely reported. An 81-year-old man was diagnosed with cerebral infarction 2 months earlier and was admitted to our hospital with rash, fever, wheezing, and stomach discomfort after being initiated with clopidogrel treatment. Based on his medical history, chest CT, and gastroscopy, we diagnosed him with clopidogrel-induced hypereosinophilic syndrome. After discontinuation of clopidogrel, the eosinophilia and symptoms improved. In cases of drug-induced eosinophilia, it is important to obtain a detailed medical history. 
546 |a EN 
690 |a eosinophilic gastroenteritis 
690 |a eosinophilic pneumonitis 
690 |a computed tomography 
690 |a hypereosinophilic syndrome 
690 |a gastroscopy 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Romanian Journal of Internal Medicine, Vol 61, Iss 4, Pp 216-221 (2023) 
787 0 |n https://doi.org/10.2478/rjim-2023-0022 
787 0 |n https://doaj.org/toc/2501-062X 
856 4 1 |u https://doaj.org/article/6e5b429e63e04e09a6dc0d02ed41c03c  |z Connect to this object online.