Proteomic analysis to identification of hypoxia related markers in spinal tuberculosis: a study based on weighted gene co-expression network analysis and machine learning

• Main Authors: Shaofeng Wu (Author), Tuo Liang (Author), Jie Jiang (Author), Jichong Zhu (Author), Tianyou Chen (Author), Chenxing Zhou (Author), Shengsheng Huang (Author), Yuanlin Yao (Author), Hao Guo (Author), Zhen Ye (Author), Liyi Chen (Author), Wuhua Chen (Author), Binguang Fan (Author), Jiahui Qin (Author), Lu Liu (Author), Siling Wu (Author), Fengzhi Ma (Author), Xinli Zhan (Author), Chong Liu (Author)
• Format: Book
• Published: BMC, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective This article aims at exploring the role of hypoxia-related genes and immune cells in spinal tuberculosis and tuberculosis involving other organs. Methods In this study, label-free quantitative proteomics analysis was performed on the intervertebral discs (fibrous cartilaginous tis...