Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the differe...

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Bibliographic Details
Main Authors: Mart A.F.J. van de Laar (Author), Inger L. Meek (Author), Harald E. Vonkeman (Author)
Format: Book
Published: MDPI AG, 2010-07-01T00:00:00Z.
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Summary:While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin.
Item Description:10.3390/ph3072146
1424-8247